According to Taiwanese researchers in an article published in the Journal of Food and drug Analysis, researchers examined the impact of consumption of Depressa peel extract ( a Japanese citrus) in a high-fat diet (HFD)-induced obese mice model, observing that the flavonoid-rich extract containing hesperidin, sinesentin, nobiletin, tangeretin, 5-demethylnobiletin, and 5-demethyltangeretin increased Lactobacillus reuteri demonstrating that the demonstrated that extract helps decrease lipid accumulation through the AMPK pathway, a prebiotic-like effect.

Original publication: https://www.jfda-online.com/journal/vol32/iss2/7/